A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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2009, discovery of a new phenotype for microorganisms in slim nanofluidic slits; and initially detection of area protein buildings together DNA applying solid-point out nanopores
You regularly get entangled in discussions about science and religion. You've got also penned many publications on the topic. Don’t you feel that at some point We are going to know every little thing Which God’s part will probably be about?
Multicolor imaging with the bacterial nucleoid and mobile division proteins with blue, orange, and close to-infrared fluorescent proteins
Because 2000, Dekker has shifted the leading focus of his operate to biophysics exactly where he reports the Qualities of solitary biomolecules and cells utilizing the applications of nanotechnology. This transformation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as through the prolonged-time period perspective that a lot of intriguing discoveries might be envisioned During this discipline.[5] Recent traces of exploration in his biophysics team are during the parts of:[six]
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Our analysis ranges through the biophysics of DNA to synthetic cells and over and above. Remember to have a look beneath in the spectrum of our existing tasks.
‘At first we looked at biological devices having a Bodily perspective and acted on the basis in the instruments we knew. It took a couple of years just before we started off working a lot more on the large Organic problems. I then started to phone it nanobiology, a time period that didn't exist at the time.
Studying DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
2003, shown the 1st biosensors designed away from a carbon nanotube; settled the structure and system of DNA mend proteins; and discovery of a whole new approach for fabricating strong-state nanopores for DNA translocation
Extremely interesting, but that wasn’t really the place my desire lay. I desired to pioneer and I experienced the sensation that was no longer attainable, as the most fascinating elementary insights experienced already been uncovered. But my area had formulated many fascinating new instruments to evaluate person molecules. I decided that I planned to utilize this to biology, to look at it from a physical perspective.’
Tests pseudotopological and nontopological designs for SMC-pushed DNA loop extrusion towards roadblock-traversal experiments
Numerous new phenomena were being learned, and he and his investigation group recognized a leading situation On this field of exploration. Dekker and his study team found new physics of nanotubes and explored the https://www.ceesdekker.net feasibility of molecular electronics. In 1998, they have been the first to create a transistor based on one nanotube molecule.
2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of lengthy-array conformational modifications in Mre11/DNA maintenance complexes; and very first pressure measurements on a DNA molecule within a nanopore
Last but not least, I'll briefly sketch several of our Thoughts to explore the developing of synthetic cells, particularly our very first methods to ascertain synthetic cell division.